Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer.

Rojas, Luis A; Sethna, Zachary; Soares, Kevin C; Olcese, Cristina; Pang, Nan; Patterson, Erin; Lihm, Jayon; Ceglia, Nicholas; Guasp, Pablo; Chu, Alexander; Yu, Rebecca; Chandra, Adrienne Kaya; Waters, Theresa; Ruan, Jennifer; Amisaki, Masataka; Zebboudj, Abderezak; Odgerel, Zagaa; Payne, George; Derhovanessian, Evelyna; Müller, Felicitas; Rhee, Ina; Yadav, Mahesh; Dobrin, Anton; Sadelain, Michel; Luksza, Marta; Cohen, Noah; Tang, Laura; Basturk, Olca; Gönen, Mithat; Katz, Seth; Do, Richard Kinh; Epstein, Andrew S; Momtaz, Parisa; Park, Wungki; Sugarman, Ryan; Varghese, Anna M; Won, Elizabeth; Desai, Avni; Wei, Alice C; D'Angelica, Michael I; Kingham, T Peter; Mellman, Ira; Merghoub, Taha; Wolchok, Jedd D; Sahin, Ugur; Türeci, Özlem; Greenbaum, Benjamin D; Jarnagin, William R; Drebin, Jeffrey; O'Reilly, Eileen M.

Nature ; 618(7963): 144-150, 2023 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-37165196

2.

Genomic profiling identifies somatic mutations predicting thromboembolic risk in patients with solid tumors.

Dunbar, Andrew; Bolton, Kelly L; Devlin, Sean M; Sanchez-Vega, Francisco; Gao, Jianjiong; Mones, Jodi V; Wills, Jonathan; Kelly, Daniel; Farina, Mirko; Cordner, Keith B; Park, Young; Kishore, Sirish; Juluru, Krishna; Iyengar, Neil M; Levine, Ross L; Zehir, Ahmet; Park, Wungki; Khorana, Alok A; Soff, Gerald A; Mantha, Simon.

Blood ; 137(15): 2103-2113, 2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33270827

3.

Targeting DNA damage repair pathways in pancreas cancer.

Crowley, Fionnuala; Park, Wungki; O'Reilly, Eileen M.

Cancer Metastasis Rev ; 40(3): 891-908, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34403012

4.

Circulating tumor and invasive cell expression profiling predicts effective therapy in pancreatic cancer.

Yu, Kenneth H; Park, Jennifer; Mittal, Avni; Abou-Alfa, Ghassan K; El Dika, Imane; Epstein, Andrew S; Ilson, David H; Kelsen, David P; Ku, Geoffrey Y; Li, Jia; Park, Wungki; Varghese, Anna M; Chou, Joanne F-L; Capanu, Marinela; Cooper, Brandon; Bartlett, Andrew; McCarthy, Devan; Sangar, Vineet; McCarthy, Brian; O'Reilly, Eileen M.

Cancer ; 128(15): 2958-2966, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-35647938

5.

Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes.

Momtaz, Parisa; O'Connor, Catherine A; Chou, Joanne F; Capanu, Marinela; Park, Wungki; Bandlamudi, Chaitanya; Berger, Michael F; Kelsen, David P; Suehnholz, Sarah P; Chakravarty, Debyani; Yu, Kenneth H; Varghese, Anna M; Zervoudakis, Alice; Li, Jia; Ku, Geoffrey Y; Park, Jennifer S; Shcherba, Marina; Harding, James J; Goldberg, Zoe; Abou-Alfa, Ghassan K; Salo-Mullen, Erin E; Stadler, Zsofia K; Iacobuzio-Donahue, Christine A; O'Reilly, Eileen M.

Cancer ; 127(23): 4393-4402, 2021 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-34351646

6.

Local Control and Survival After Induction Chemotherapy and Ablative Radiation Versus Resection for Pancreatic Ductal Adenocarcinoma With Vascular Involvement.

Jolissaint, Joshua S; Reyngold, Marsha; Bassmann, Jared; Seier, Kenneth P; Gönen, Mithat; Varghese, Anna M; Yu, Kenneth H; Park, Wungki; O'Reilly, Eileen M; Balachandran, Vinod P; D'Angelica, Michael I; Drebin, Jeffrey A; Kingham, T Peter; Soares, Kevin C; Jarnagin, William R; Crane, Christopher H; Wei, Alice C.

Ann Surg ; 274(6): 894-901, 2021 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-34269717

7.

Leptomeningeal disease in pancreas ductal adenocarcinoma: A manifestation of longevity.

O'Connor, Catherine A; Park, Jennifer S; Kaley, Thomas; Kezlarian, Brie; Edelweiss, Marcia; Yang, T Jonathan; Park, Wungki; Reidy, Diane; Varghese, Anna M; Yu, Kenneth H; O'Reilly, Eileen M.

Pancreatology ; 21(3): 599-605, 2021 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-33582005

8.

Pancreatic Cancer: A Review.

Park, Wungki; Chawla, Akhil; O'Reilly, Eileen M.

JAMA ; 326(9): 851-862, 2021 09 07.

Artigo em Inglês | MEDLINE | ID: mdl-34547082

9.

Alterations in driver genes are predictive of survival in patients with resected pancreatic ductal adenocarcinoma.

McIntyre, Caitlin A; Lawrence, Sharon A; Richards, Allison L; Chou, Joanne F; Wong, Winston; Capanu, Marinela; Berger, Michael F; Donoghue, Mark T A; Yu, Kenneth H; Varghese, Anna M; Kelsen, David P; Park, Wungki; Balachandran, Vinod P; Kingham, T Peter; D'Angelica, Michael I; Drebin, Jeffrey A; Jarnagin, William R; Iacobuzio-Donahue, Christine A; Allen, Peter J; O'Reilly, Eileen M.

Cancer ; 126(17): 3939-3949, 2020 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-32573775

10.

Association of the prognostic model iSEND with PD-1/L1 monotherapy outcome in non-small-cell lung cancer.

Park, Wungki; Mezquita, Laura; Okabe, Naoyuki; Chae, Young Kwang; Kwon, Deukwoo; Saravia, Diana; Auclin, Edouard; Planchard, David; Caramella, Caroline; Ferrara, Roberto; Agte, Sarita; Oh, Michael; Mudad, Raja; Jahanzeb, Mohammad; Suzuki, Hiroyuki; Besse, Benjamin; Lopes, Gilberto.

Br J Cancer ; 122(3): 340-347, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-31761899

11.

Correction to: Outcomes associated with immune-related adverse events in metastatic non-small cell lung cancer treated with nivolumab: a pooled exploratory analysis from a global cohort.

Naqash, Abdul Rafeh; Ricciuti, Biagio; Owen, Dwight H; Florou, Vaia; Toi, Yukihiro; Cherry, Cynthia; Hafiz, Maida; De Giglio, Andrea; Muzaffar, Mavish; Patel, Sandip H; Sugawara, Shunichi; Burkart, Jarred; Park, Wungki; Chiari, Rita; Sugisaka, Jun; Otterson, Gregory A; de Lima Lopes, Gilberto; Walker, Paul R.

Cancer Immunol Immunother ; 69(7): 1189, 2020 07.

Artigo em Inglês | MEDLINE | ID: mdl-32347358

12.

Outcomes associated with immune-related adverse events in metastatic non-small cell lung cancer treated with nivolumab: a pooled exploratory analysis from a global cohort.

Naqash, Abdul Rafeh; Ricciuti, Biagio; Owen, Dwight H; Florou, Vaia; Toi, Yukihiro; Cherry, Cynthia; Hafiz, Maida; De Giglio, Andrea; Muzaffar, Mavish; Patel, Sandip H; Sugawara, Shunichi; Burkart, Jarred; Park, Wungki; Chiari, Rita; Sugisaka, Jun; Otterson, Gregory A; de Lima Lopes, Gilberto; Walker, Paul R.

Cancer Immunol Immunother ; 69(7): 1177-1187, 2020 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-32140762

13.

Axitinib plus pembrolizumab in patients with advanced sarcomas including alveolar soft-part sarcoma: a single-centre, single-arm, phase 2 trial.

Wilky, Breelyn A; Trucco, Matteo M; Subhawong, Ty K; Florou, Vaia; Park, Wungki; Kwon, Deukwoo; Wieder, Eric D; Kolonias, Despina; Rosenberg, Andrew E; Kerr, Darcy A; Sfakianaki, Efrosyni; Foley, Mark; Merchan, Jaime R; Komanduri, Krishna V; Trent, Jonathan C.

Lancet Oncol ; 20(6): 837-848, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-31078463

14.

Clinical Implications of Circulating Tumor DNA Tumor Mutational Burden (ctDNA TMB) in Non-Small Cell Lung Cancer.

Chae, Young Kwang; Davis, Andrew A; Agte, Sarita; Pan, Alan; Simon, Nicholas I; Iams, Wade T; Cruz, Marcelo R; Tamragouri, Keerthi; Rhee, Kyunghoon; Mohindra, Nisha; Villaflor, Victoria; Park, Wungki; Lopes, Gilberto; Giles, Francis J.

Oncologist ; 24(6): 820-828, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-30867242

15.

The Concept of Biosimilars: From Characterization to Evolution-A Narrative Review.

Farhat, Fadi; Torres, Alfredo; Park, Wungki; de Lima Lopes, Gilberto; Mudad, Raja; Ikpeazu, Chukwuemeka; Abi Aad, Simon.

Oncologist ; 23(3): 346-352, 2018 03.

Artigo em Inglês | MEDLINE | ID: mdl-29284760

16.

Long-term survival based on pathologic response to neoadjuvant therapy in esophageal cancer.

Tiesi, Gregory; Park, Wungki; Gunder, Meredith; Rubio, Gustavo; Berger, Michael; Ardalan, Bach; Livingstone, Alan; Franceschi, Dido.

J Surg Res ; 216: 65-72, 2017 08.

Artigo em Inglês | MEDLINE | ID: mdl-28807215

17.

A Review of Pancreatic Cancer-Reply.

Park, Wungki; Chawla, Akhil; O'Reilly, Eileen M.

JAMA ; 326(23): 2436-2437, 2021 12 21.

Artigo em Inglês | MEDLINE | ID: mdl-34932080

18.

Heat shock protein 90 promotes epithelial to mesenchymal transition, invasion, and migration in colorectal cancer.

Nagaraju, Ganji Purnachandra; Long, Tua-Elisabeth; Park, Wungki; Landry, Jerome C; Taliaferro-Smith, LaTonia; Farris, Alton B; Diaz, Roberto; El-Rayes, Bassel F.

Mol Carcinog ; 54(10): 1147-58, 2015 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-24861206

19.

Precision medicine for pancreatic cancer: Characterizing the clinico-genomic landscape and outcomes of KRAS G12C-mutated disease.

Keane, Fergus; Chou, Joanne F; Walch, Henry; Schoenfeld, Joshua; Singhal, Anupriya; Cowzer, Darren; Harrold, Emily; O'Connor, Catherine; Park, Wungki; Varghese, Anna; El Dika, Imane; Balogun, Fiyinfolu; Yu, Kenneth H; Capanu, Marinela; Schultz, Nikolaus; Yaeger, Rona; O'Reilly, Eileen M.

J Natl Cancer Inst ; 2024 May 03.

Artigo em Inglês | MEDLINE | ID: mdl-38702822

20.

Concordance in Oncogenic Alterations Between the Primary Tumor and Advanced Disease: Insights Into the Heterogeneity of Intrahepatic Cholangiocarcinoma.

McIntyre, Sarah M; Preston, William A; Walch, Henry; Sharib, Jeremy; Kundra, Ritika; Sigel, Carlie; Lidsky, Michael E; Allen, Peter J; Morse, Michael A; Chen, Wei; Cercek, Andrea; Harding, James J; Abou-Alfa, Ghassan K; O'Reilly, Eileen M; Park, Wungki; Balachandran, Vinod P; Drebin, Jeffrey; Soares, Kevin C; Wei, Alice; Kingham, T Peter; D'Angelica, Michael I; Iacobuzio-Donahue, Christine; Jarnagin, William R.

JCO Precis Oncol ; 8: e2300534, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38394469

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